The competence centers at OTH Regensburg represent interdisciplinary and cross-faculty research units. Topics relevant to research strategy are institutionalized under the umbrella of the centers. An extensive network of researchers ensures the appropriate depth, breadth and continuity of the research topics dealt with. These research units exist:

• Combustion Engines and Emissions Control Laboratory - CEEC
• Competence Center Software Engineering - CCSE
• Historical Building Research - HB
• Friedrich Mielke Institute for Scalalogy - FMIS
• Innovation Center for Production Logistics and Factory Planning - IPF
• Institute for Social Research and Technology Assessment - IST
• LandUmbau
• Laboratory for Safe and Secure Systems - LaS³
• Mechatronics Research Unit - MRU
• Sustainable Building - KNB
• Nanoanalytics and Semiconductor Chemistry - Nanochem
• Sensor Application Center - SappZ